Cardarine (GW501516) Review – Should You Really Use It For BodyBuilding ?

While discussing about SARMs (Selective Androgen Receptor Modulator) you would have often come across the compound, Cardarine, as these drugs are commonly stacked with SARMs.


These stacks are becoming increasingly popular among bodybuilders and athletes. So, what is Cardarine? Is it a SARM too? What are its benefits? Does it have any side effects?

Let us look into these aspects of this specific chemical compound. This article will give answers to all the above questions.

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What is Cardarine GW 501516 Used For?

Cardarine is also known as Endurobol or GW – 501516. Cardarine is a performance enhancer and is often mistaken to be a SARM by a majority of the people. But it is not a SARM.

Unlike SARM, Cardarine is a PPARδ (Peroxisome Proliferator-Activated Receptor) receptor agonist that was developed by Ligand Pharmaceuticals and GlaxoSmithKline.Cardarine SupplementCardarine binds to these PPARδ receptors, which are a group of nuclear proteins found in muscles and fatty acids in the body.

Hence, these receptors get activated and help the body to burn fat, increase muscle endurance, and build lean muscle. It also has a positive effect on your vascular system.

What Does Cardarine Contains?

Cardarine is a synthetic substance made of monocarboxylic acid Which is commonly known as Endurobol. It is a chemical member of 1,3-thiazoles belonging to an organofluorine compound, an aromatic ether and an aryl sulfide. 

It do not contain any herbal or natural ingredients and hence is prone to severe side effects. 

Cardarine claims to be an orally active drug but being a synthetic composition, it is not fit for normal digestion process. It takes a toll on vital organs when abused or consumed regularly or for long duration.

Why Is Cardarine GW-501516 Illegal?

Cardarine is PPAR and hence is a under research drug. Its use is not completely approved for humans. Being under research substance, it is extensively studied over animals for numerous disease and inabilities. 

It do have some proven results in terms of clinical treatments when conducted on animals, however those are not proven on humans and thus it is not recommended for any kind of medical use by .

Owing to its positive results while research, it became famous for boosting energy. Hence Athletes and body builders have started abusing it to gain instant and powerful results.

Which further led to severe damage for their vital organs hence it is banned by WADA for use among humans, making it illegal to posses and use.

How Long Does Cardarine Stay In Your System?

Generally SARMs stays quite a long in the body and takes time to flush out of our system. Cardarine GW501516 have a half life of approximately 24 hours. 

That means it stays in your body for 24 hours and participate in all functions. Active stay of any such powerful drug within body may leads to damage causing effects for Vital organs.

Hence FDA disapproved its common usage as orally active supplement. 

What Does Cardarine Do To The Body?

  • Cardarine lowers LDL cholesterol levels and thus, decreases the risk of heart attacks.
  • As it activates the PPARδ receptor, it has anti-inflammatory properties that reduce the oxidative damage to the blood vessels and tissues.
  • The anti-inflammatory properties of Cardarine also prevent brain cells from oxidative stress and help reduce kidney inflammations.
  • It enhances nitric oxide levels in your arteries thereby, increasing vascularity and improving the wound healing process.
  • Due to increased vascularity, it helps in boosting your endurance levels allowing you to prolong your workouts.
  • Cardarine suppresses the glucose metabolism in the liver as it helps in switching the energy source from glucose to fatty acids. Therefore, it boosts the fat-burning ability of your body and also inhibits insulin resistance.
  • Cardarine also has a slight ability to enhance lean muscle mass, but the results are ameliorated when it is stacked with SARMs.
  • There is no requirement of a Post Cycle Therapy after using Cardarine as it does not cause any reduction in your testosterone levels. Cardarine can also be used during PCT after a SARM cycle, to avoid gaining body fat.

Cardarine (GW-501516) Dosage

The recommended dosage of Cardarine is 10-20 mg per day for 6-8 weeks. However, it is advised that beginners start the dosage at 10mg and increase it by 5mg after every cycle.

When taken alone, there is no requirement of a PCT (Post Cycle Therapy) as Cardarine does not lower testosterone levels in your body.

For optimum results, Cardarine is stacked with SARMs such as Ostarine, Andarine, Ligandrol, or RAD-140 depending on what you are trying to achieve, whether it is bulking or cutting.

Cardarine is also recommended during PCT after a SARM cycle to enhance your stamina and metabolism and thereby, avoiding fat rebound.

Does Cardarine (GW-501516) Have Side Effects?

Cardarine is prohibited under WADA Prohibited List. It is also not legal to use it in any dietary supplement or in medication.

Cardarine has been a controversial drug since a few studies conducted on mice have shown that it can cause several types of cancer.

It also accelerates a cancerous tumor as it increases its vascularity. Researches on animals have also demonstrated that Cardarine worsens a pre-existing liver condition.

It can also impair fetal development and hence, pregnant women are advised not to use it.

As a result of these findings, companies have halted their researches on humans.

It has neither been approved by the Food and Drug Administration of America (FDA) nor by the World Anti-doping Agency (WADA) due to the controversial side effects.

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Being a synthetic and illegal supplement, Cardarine is not all recommended for regular use. If you are looking for supplements that could help you achieve your body building goals and should be safe and legal, then below mentioned are alternatives to Cardarine.

These are products claim to have all natural composition and legal to posses. Manufacturers of Testoprime and TestoMax do reveals the details about the natural salts and herbs that these supplements comprise of.

You could end up getting better results than Cardarine without harming yourself just by using these safe to consume supplements.

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